Fig. 2
From: Self-Assembled Peptides: Characterisation and In Vivo Response
a Shows the molecular arrangement of a π–β fibril formed from fmoc-FF. Red indicates the inclusion of the fmoc-RGD motif. Reprinted from Ref. [38]. Copyright (2009), with permission from Elsevier. b The anti-parallel β-sheet motif of (RADA)3 (pink arrows) allows the bioactive epitope of IKVAV (blue) to be ordered within the nanoscale structure. Reprinted with permission from Ref. [21]. c Through the inclusion of a heparin-binding motif to a peptide amphiphile, heparin is recruited post-assembly to the surface of the nanostructure. Reprinted with permission from Ref. [73]. Copyright (2006) American Chemical Society. d Nanoscale fibrils of Q11-RGDS and Q11-IKVAV peptides visualized by TEM shows the underlying fibrillar structure of the hydrogel. Reprinted from Ref. [20]. Copyright (2009) with permission from Elsevier. e Individual fibrils intertwine to form a scaffold as evidenced here by atomic force microscopy image of an fmoc-peptide/protein hybrid matrix. Reprinted from Ref. [23]. Copyright (2011), with permission from Elsevier