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Biointerphases

Journal for Biophysical Chemistry

Table 1 Summary of the loading efficiency of DOX molecules into dcBSA-147-PEO(5000)28 micelles

From: Nano-Sized Albumin-Copolymer Micelles for Efficient Doxorubicin Delivery

Ratio added DOX/(2)a

Loading efficiency (Molar ratio)b

Loading efficiency (in wt%)c

Encapsulation efficiency of DOX (%)d

1:1

0.5 ± 0.1

0.15 ± 0.03

51.6 ± 9.9

5:1

1.2 ± 0.1

0.34 ± 0.01

23.1 ± 1.0

10:1

1.8 ± 0.2

0.52 ± 0.07

17.2 ± 2.3

20:1

4.3 ± 0.8

1.22 ± 0.23

20.4 ± 3.9

50:1

8.2 ± 1.1

2.33 ± 0.31

15.5 ± 2.0

100:1

13.7 ± 2.2

3.91 ± 0.63

13.1 ± 2.1

  1. aMolar ratio of feed DOX added versus dcBSA-147-PEO(5000)28 (2) for micelle formation
  2. bMolar ratio of DOX loaded into dcBSA-147-PEO(5000)28 micelles
  3. cWeight percentage of DOX loaded into dcBSA-147-PEO(5000)28 micelles
  4. dWeight percentage of loaded DOX to added DOX (feed DOX)
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