Journal for Biophysical Chemistry

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Open Access

Monitoring kinetics of surface initiated atom transfer radical polymerization by quartz crystal microbalance with dissipation

  • Hongwei Ma1,
  • Marcus Textor3,
  • Robert L. Clark4 and
  • Ashutosh Chilkoti5Email author

Received: 1 February 2006

Accepted: 1 March 2006


This article reports that the kinetics of surface-initiated atom transfer radical polymerization can be quantified by the quartz crystal microbalance with dissipation (QCM-D) technique. The kinetics of in situ growth of poly(oligoethylene glycol methylmethacrylate) monitored on a gold-coated QCM-D sensor chip revealed that changes in the experimentally observed frequency (ΔF) and dissipation (ΔD) as a function of polymerization time were a function of the initiator density, and that the experimental response could be predicted from a continuum model.