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Journal for Biophysical Chemistry

Optical sensors based on spectroscopy of localized surface plasmons on metallic nanoparticles: Sensitivity considerations

Abstract

Surface plasmon resonance (SPR) sensors use two types of surface plasmons: (i) propagating along a metal-dielectric interface and (ii) localized on metallic nano-objects. This article presents theoretical analysis of sensitivity of SPR sensors based on spectroscopy of localized surface plasmons on metallic nanoparticles. Analytical formulas inter-relating bulk and surface refractive index sensitivity with main design parameters are derived using the electrostatic approximation. The effect of particle diameter is accounted for by means of Mie theory. Figures of merit for SPR sensors using localized and propagating surface plasmons are calculated and compared. Although sensors based on spectroscopy of localized surface plasmons on gold spherical particles show promise for detection of processes occurring in the close proximity of the particle surface, their performance is still inferior to that of SPR sensors based on spectroscopy of propagating surface plasmons.

References

  1. 1

    J. Homola, Chem. Rev. (Washington, D.C.) 108, 462 (2008).

    CAS  Google Scholar 

  2. 2

    2 M. E. Stewart, C. R. Anderton, L. B. Thompson, J. Maria, S. K. Gray, J. A. Rogers, and R. G. Nuzzo, Chem. Rev. (Washington, D.C.) 108, 494 (2008).

    CAS  Google Scholar 

  3. 3

    K. A. Willets and R. P. Van Duyne, Annu. Rev. Phys. Chem. 58, 267 (2007).

    Article  CAS  Google Scholar 

  4. 4

    A. J. Haes and R. P. Van Duyne, Anal. Bioanal. Chem. 379, 920 (2004).

    Article  CAS  Google Scholar 

  5. 5

    A. D. Boardman, Electromagnetic Surface Modes (Wiley, New York, 1982).

    Google Scholar 

  6. 6

    C. F. Bohren and D. R. Huffman, Absorption and Scattering of Light by Small Particles (Wiley, New York, 1983).

    Google Scholar 

  7. 7

    E. Hutter and J. H. Fendler, Adv. Mater. (Weinheim, Ger.) 16, 1685 (2004).

    Article  CAS  Google Scholar 

  8. 8

    M. M. Miller and A. A. Lazarides, J. Phys. Chem. B 109, 21556 (2005).

    Article  CAS  Google Scholar 

  9. 9

    K. S. Lee and M. A. El-Sayed, J. Phys. Chem. B 110, 19220 (2006).

    Article  CAS  Google Scholar 

  10. 10

    H. X. Xu and M. Kall, Sens. Actuators B 87, 244 (2002).

    Article  Google Scholar 

  11. 11

    C. Sonnichsen, B. M. Reinhard, J. Liphardt, and A. P. Alivisatos, Nat. Biotechnol. 23, 741 (2005).

    Article  Google Scholar 

  12. 12

    A. J. Haes and R. P. Van Duyne, J. Am. Chem. Soc. 124, 10596 (2002).

    Article  CAS  Google Scholar 

  13. 13

    N. Nath and A. Chilkoti, Anal. Chem. 76, 5370 (2004).

    Article  CAS  Google Scholar 

  14. 14

    J. C. Riboh, A. J. Haes, A. D. McFarland, C. R. Yonzon, and R. P. Van Duyne, J. Phys. Chem. B 107, 1772 (2003).

    Article  CAS  Google Scholar 

  15. 15

    M. D. Malinsky, K. L. Kelly, G. C. Schatz, and R. P. Van Duyne, J. Phys. Chem. B 105, 2343 (2001).

    Article  CAS  Google Scholar 

  16. 16

    C. Mätzler, “MATLAB Functions for Mie Scattering and Absorption,” Institut für Angewandte Physik, Bern, Switzerland, Report No. 2002-08, 2002.

    Google Scholar 

  17. 17

    D. R. Lide, CRC Handbook of Chemistry and Physics (CRC, Boca Raton, FL, 1998).

    Google Scholar 

  18. 18

    Optical constants database available from SOPRA SA, France at http://www.sopra-sa.com/index2.php?goto=dlrub=4

  19. 19

    C. D. Chen, S. F. Cheng, L. K. Chau, and C. R. C. Wang, Biosens. Bioelectron. 22, 926 (2007).

    Article  CAS  Google Scholar 

  20. 20

    J. Homola, Surface Plasmon Resonance Based Sensors (Springer, Berlin, 2006).

    Book  Google Scholar 

  21. 21

    P. B. Johnson and R. W. Christy, Phys. Rev. B 6, 4370 (1972).

    Article  CAS  Google Scholar 

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Kvasnička, P., Homola, J. Optical sensors based on spectroscopy of localized surface plasmons on metallic nanoparticles: Sensitivity considerations. Biointerphases 3, FD4–FD11 (2008). https://doi.org/10.1116/1.2994687

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