Journal for Biophysical Chemistry

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Open Access

Cutin synthesis: A slippery paradigm

  • Antonio Heredia1Email author,
  • José A. Heredia-Guerrero1,
  • Eva Domínguez2 and
  • José J. Benítez3

Received: 28 October 2008

Accepted: 5 December 2008


Despite its biological importance, the mechanism of construction of cutin, the polymer matrix of plant cuticles, has not yet been elucidated. Recently, progress on lipid barrier formation of polymers such as cutin and suberin has been recently reviewed by Pollard et al. 1 In their review the authors state that the ubiquitous cutin is the least understood of the plant extracellular polymers and that major questions about cutin structure and its macromolecular assembly remain to be resolved. At the time this paper was being published our research group has developed a new hypothesis on plant cutin synthesis.2