Figure 3
From: Cell membrane topology analysis by RICM enables marker-free adhesion strength quantification
Cell adhesion kinetics. RICM images and corresponding threshold images at various stages of cell spreading for PatuT (A) and PatuS cells (B) at 16, 30, and 60 min post plating (Scale bar: 10 μm). Cell spreading kinetics for the average projected cell area (C) and the average adhesion area (D) of the two cell lines. Error bars represent the standard errors of the mean (SEM). Characteristic normalized intensity profile plots (E) of the interface of a typical PatuT (top) and PatuS (bottom) cell for the same time points are shown. The distances are color-coded from close (blue) to far (red).