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Journal for Biophysical Chemistry

Figure 2 | Biointerphases

Figure 2

From: Studying the penetration of fatty acids into human skin by ex vivo TOF-SIMS imaging

Figure 2

Optical and mass spectrometry images of human skin sections. a, d, g and j: Optical pictures of transversal human skin sections; b, e, h and k: TOF-SIMS images (negative ion mode) showing lateral distribution of capric, lauric, linoleic and oleic acid ions in skin treated with 10% fatty acid solution; c, f, i and l: TOF-SIMS images (negative ion mode) showing lateral distribution of capric, lauric, linoleic and oleic acid ions in control skin. Field of view 1.5 × 0.5 mm2, 750 × 250 pixels, pixel size 2 × 2 μm2, fluence 5 × 1011 ions/cm2. The amplitude of the color scale corresponds to the maximum number of counts mc and could be read as [0, mc]. tc is the total number of counts recorded for the specified m/z (the sum of counts in all pixels).

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