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Biointerphases

Journal for Biophysical Chemistry

Table 1 Amount of tolnaftate in human epidermis quantified by a validated HPLC-UV method, and enhancing ratios of fatty acids

From: Studying the penetration of fatty acids into human skin by ex vivo TOF-SIMS imaging

Donor phase

T amount, μg/cm2± SD, n=3 (epidermis)

ER (epidermis)

Control solution

2.56 ± 0.15

-

With 10% oleic acid

4.77 ± 0.79

1.86Ù­

With 10% linoleic acid

2.61 ± 0.32

1.02

With 10% lauric acid

3.06 ± 0.32

1.20

With 10% capric acid

2.42 ± 0.40

0.95

  1. Abbreviations: T, tolnaftate; ER, enhancing ratio.
  2. Ù­Siginificant difference at P < 0.05.
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